Rewind the clock

What if you had the dementia risk and mental sharpness of someone 10-20 years younger?
See how BetterBrain can help

Your BetterBrain journey

Brain health in today's healthcare system is full of outdated practices, long lines, and unnecessary complexity.
BetterBrain complements your existing clinical care and makes the cutting edge simple and accessible.
health assessment
Step 1

Establish a baseline

Start by completing your health questionnaire and cognitive test. Get your blood draw from a local lab, or have a licensed phlebotomist come to your home (where available).
results
Step 2

Understand and plan

Visualize your results and see your top opportunities in plain English. Create a personalized protocol that fits your biology, constraints, and lifestyle.
action plan
Step 3

Act on your plan

Put your plan into practice and let us help you stay on track. Access curated products and more advanced clinical services if needed.
reassess and adapt
Step 4

Retest and adapt

Retest your most critical markers after 3 months to see your progress and adapt your plan accordingly.

BetterBrain in practice

Insights

Get a comprehensive and convenient brain check-up
blood biomarkers
50+ blood biomarkers
Get tested for 50+ brain health biomarkers curated by physicians, with the option for at-home testing
See more
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follow up diagnostics
Follow up re-testing
Re-testing of any biomarkers that were sub-optimal in your baseline at no additional cost, plus any other diagnostics needed
See more
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cognitive assessments
Unlimited cognitive assessments
Unlimited access to 15-minute scientifically validated, gamified test
See more
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Optional pTau-217 testing
Get the most accurate view of your current dementia risk up to 20 years before symptoms occur
See more
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Improve

Act on your results using a tailored protocol and expert guidance
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Results dashboard
Understand your health with plain english interpretations, visualize your  biology, and track your results
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expert consultation
Expert guidance
75-minute 1:1 session with a brain health expert or in-depth reporting to understand your results and co-create your protocol
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expert consultation
Unlimited messaging
On-demand live chat with our brain health experts
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BetterBrain’s approach to brain health

Achieving brain health requires a deep, holistic understanding of your health and using evidence based practices to improve your well-being and reduce risk.

Insights
Brain health and dementia risk are best understood using four complementary lenses.
Each lens helps identify risks, prioritize actions to take, and track whether those actions are working.
Improve
Brain function & dementia risk can be substantially improved using  5 principles, which are divided into 11 practices.
They are especially powerful when used together and are tailored to specific risk factors.

Brain physiology

Brain specific-markers including amyloid and tau levels, blood flow,  neurotransmitter activity, brain volume, and signs of damage.

Whole-body health

A biomarker-based understanding of the 10 bodily systems that most impact dementia risk and well-being

Cognitive performance

An objective understanding of how well you currently think, remember, and solve problems

Daily function

Your mood, clarity, energy, mobility, and the absence of unfavorable symptoms

Engagement

Engagement is about what we do, not what we avoid. Using our brains to learn, relate to others, and move our bodies can have a profoundly positive impact on our brains.

Nourishment

Nourishment is about eating the right food in the right quantity and supplementing when needed.

Restoration

Our bodies and brains also need restoration, primarily by sleeping well but also by reducing our stress levels.

Protection

Protecting our brains means defending it from harm, whether direct or indirect, and minimizing exposure to the most harmful environmental toxins.

Treatment

Treating acute medical issues maintain your body and your brain. It’s important to use the most effective clinical therapies, including prescription drugs.

Brain physiology

Whole body health

Cognitive Performance

Daily Function

Engagement

Move
Relate
Learn

Nourishment

Supplement
Eat

Restoration

Sleep
De-stress

Protection

Defend
Environment

Treatment

Drugs
Therapy

Hover over boxes to see more about how BetterBrain uses the science of Insights and Improve to approach brain health

BetterBrain in action

No two approaches are the same

Joan, 59

Risks uncovered
High ptau-217
Poor fitness
HSV-1 infection
No flu vaccination
High LDL-C & ApoB
Action Plan
  • You fit the criteria for a clinical trial on Leqembi effectiveness before dementia symptoms occur - we can find time to share details
  • Talk to your PCP about starting lipid lowering therapy to mitigate your diabetes progression
  • Start getting a flu vaccine annually - BetterBrain will find a location near you
  • Bike at zone 2 for 45 minutes twice a week
  • Brush off your piano and consider lessons
3-month follow-up
  • Successfully enrolled in AHEAD 3-45 trial
  • Started on a low dose of Rosuvastatin
  • pTau-217 reduced to less concerning levels
  • LDL-C lowered by 28%
  • Received a flu vaccine
Action Plan
  • You fit the criteria for a clinical trial on Leqembi effectiveness before dementia symptoms occur - we can find time to share details
  • Talk to your PCP about starting lipid lowering therapy to mitigate your diabetes progression
  • Start getting a flu vaccine annually - BetterBrain will find a location near you
  • Bike at zone 2 for 45 minutes twice a week
  • Brush off your piano and consider lessons
3-month follow-up
  • Successfully enrolled in AHEAD 3-45 trial
  • Started on a low dose of Rosuvastatin
  • pTau-217 reduced to less concerning levels
  • LDL-C lowered by 28%
  • Received a flu vaccine

Amit, 61

Risks uncovered
High ptau-217
Low Vitamin D
High homocysteine
Low concentration
Poor short-term memory
Action Plan
  • Your tests indicate you may be in the early stages of dementia - a patient advocate connect you with a neurologist for next steps
  • Start Vitamin D and B12 supplementation
  • Use a sauna for 20m daily, ideally within 2 hours of bed
  • Experiment with a ketogenic diet
3-month follow-up
  • Approved for & started Leqembi within 30 days
  • Improved memory, concentration, and reasoning scores
  • Reduced homocysteine to optimal levels
  • Reported falling asleep faster and feeling better rested in the mornings
Action Plan
  • Your tests indicate you may be in the early stages of dementia - a patient advocate connect you with a neurologist for next steps
  • Start Vitamin D and B12 supplementation
  • Use a sauna for 20m daily, ideally within 2 hours of bed
  • Experiment with a ketogenic diet
3-month follow-up
  • Approved for & started Leqembi within 30 days
  • Improved memory, concentration, and reasoning scores
  • Reduced homocysteine to optimal levels
  • Reported falling asleep faster and feeling better rested in the mornings

Nancy, 67

Risks uncovered
Poor fitness
High homocysteine
Low Omega-3 ratio
Elevated HbA1c
Chronic anticholinergic use
Action Plan
  • Talk to your PCP about starting treatment for your diabetes; BetterBrain will share a sheet with important questions to cover
  • Engage in 1 HIIT session and 2 full-body strength training sessions per week
  • Start fish oil and methyl-B supplements
  • Start using Xyzal instead of Benadryl to cut your exposure to harmful anticholinergics
3-month follow-up
  • Immediately switched from Benadryl to Xyzal
  • Started on Metformin after talking to PCP
  • HbA1c levels reduced topre-diabetic
  • Reduced homocysteine to optimal levels
  • Improved omega-3 ratio
Action Plan
  • Talk to your PCP about starting treatment for your diabetes; BetterBrain will share a sheet with important questions to cover
  • Engage in 1 HIIT session and 2 full-body strength training sessions per week
  • Start fish oil and methyl-B supplements
  • Start using Xyzal instead of Benadryl to cut your exposure to harmful anticholinergics
3-month follow-up
  • Immediately switched from Benadryl to Xyzal
  • Started on Metformin after talking to PCP
  • HbA1c levels reduced topre-diabetic
  • Reduced homocysteine to optimal levels
  • Improved omega-3 ratio

FAQs

Are Alzheimer's disease and other dementias preventable?

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While there is no cure for Alzheimer's disease, the science around prevention has progressed tremendously over the past few years, as detailed in our Science section. A landmark study suggested that ~40% of cases are preventable, but many experts believe this might be closer to 60% given they did not consider important factors such as sleep, hyperhomocysteinemia, among others. What's more, implementing these brain health strategies has clear short term cognitive benefits (25% improvement per the landmark FINGER study) and improves many other aspects of your health.

What are some things I can do to reduce my risk of developing dementia?

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While it may not be satisfying, the reality is that "it depends". There are 100+ potential interventions, but to find the 3-5 most effective ones it is critical to understand your biology — hence why BetterBrain does extensive blood biomarker testing among other assessments.

How do you keep my health information safe?

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We know your health data is some of your most valuable information. That's why we hold a high bar for data privacy and security, and composed a team of experienced leaders who have built secure data systems in the past:

  • One of our co-founders built a secure healthcare platform containing data from over 140M Americans and 7 of the largest health systems in the country
  • Our chief engineer built the data infrastructure that housed 15% of all COVID test results in the US, including for members of congress and the Department of Defense. Through his work with electronic health record companies, he ensured the security of ~10% of the US population's healthcare data.

All of BetterBrain's staff are trained on HIPAA regulations, and we use these experts' technical knowledge to constantly enhance our digital, physical, and administrative security measures.

Please refer our privacy notice for more information.

Is BetterBrain right for me?

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BetterBrain was designed for anyone interested in improving their brain health — both reducing dementia risk and improving cognitive function. We find that people who benefit the most typically have  (1) a family history of dementia / Alzheimer's, OR (2) 1 or 2 copies of the APOE4 gene, OR (3) have been experiencing some level of cognitive decline they would like to address.

I already have my own doctor, how does BetterBrain fit in?

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BetterBrain aims to integrate seamlessly into your existing care and help you navigate the broader healthcare system. We do not intend to replace the work of your physician and believe it is important for all to maintain a relationship with a primary care doctor and/or a neurologist.

Does BetterBrain diagnose Alzheimer's or other dementias?

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Although BetterBrain can help you unlock a wealth of data about your health and biology, we do not diagnose any conditions. In other words, BetterBrain is not a substitute to medical care. Instead, we encourage to you use the information you learn through BetterBrain to have a thoughtful discussion with your physician to receive any diagnoses and come up with a clinical path forward.

I get lab tests every year at my annual physical. How is this different?

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BetterBrain's battery of tests is completely different than what primary care physicians typically order. Our panel has been carefully assembled and vetted by leading physicians to provide a comprehensive view of your brain health. Unfortunately, many of these tests are inaccessible to most people given doctors are typically less focused on long term prevention, and insurance companies require "medical necessity" which usually requires existing symptoms.

What tests do you perform? 

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One of the first steps in your BetterBrain journey is to get a series of tests to help you identify your brain health risks. The tests included in your membership fall under two categories.

Cognitive assessments
Our battery of cognitive tests is designed to give you quick insights on different types of brain abilities - memory, reasoning, concentration, and verbal abilities. These tests have been designed based off 30+ years of research an are used by over 10,000 providers around the world. You can read more about our cognitive testing on our testing partner's website.

Blood tests
Our panel of cross-specialty physicians assembled a set of 54 biomarkers that are the most important to understand for your brain health. We test all of these markers in your initial blood panel, and re-test your most urgent markers after ~3 months at no additional cost.
  • Albumin
  • Albumin : globulin ratio
  • Alkaline phosphate
  • Apolipoprotein B
  • Aspartate aminotransferase (AST)
  • Baso (Absolute)
  • Basos
  • Bilirubin
  • BUN
  • BUN : creatinine ratio
  • Calcium
  • Carbon dioxide
  • Chloride
  • Creatinine
  • EGF
  • Eosinophils (Absolute)
  • Eosinophils
  • Ferritin
  • Folate (Folic Acid)
  • Globulin
  • Glucose
  • HDL cholesterol
  • Hematocrit
  • Hemoglobin
  • Hemoglobin A1c
  • hs-CRP
  • Homocysteine
  • Immature Granulocytes
  • Immature Grans (Abs)
  • Insulin
  • LDL cholesterol
  • Lipoprotein (a)
  • Lymphocytes
  • Lymphocytes (Absolute)
  • MCH
  • MCHC
  • MCV
  • Monocytes
  • Monocytes (Absolute)
  • Neutrophils
  • Neutrophils (Absolute)
  • Platelets
  • Potassium
  • RBC
  • RDW
  • Serum protein
  • Sodium
  • Triglycerides
  • TSH
  • Uric acid
  • VLDL cholesterol
  • Vitamin B12
  • Vitamin D 25-OH
  • WBC
  • Vitamin B12
  • Albumin
  • Albumin : globulin ratio
  • Alkaline phosphate
  • Aspartate aminotransferase (AST)
  • Bilirubin
  • BUN
  • BUN : creatinine ratio
  • Calcium
  • Carbon dioxide
  • Apolipoprotein B
  • Chloride
  • Creatinine
  • eGFR
  • Ferritin
  • Globulin
  • Glucose
  • HDL cholesterol
  • Hemoglobin A1c
  • High Sensitivity C-Reactive Protein
  • Homocysteine
  • Insulin
  • LDL cholesterol
  • Potassium
  • Serum protein
  • Sodium
  • Triglycerides
  • TSH
  • Vitamin B12
  • Vitamin D 25-OH
  • VLDL cholesterol
Although there are many more tests you can do that are relevant to your brain health, they are often more expensive and more targeted. BetterBrain can help you access deeper testing at a discounted fee.

How soon after joining can I get tested?

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Typically within a few days. As soon as you're signed up, you can schedule your mobile phlebotomy appointment. You can also complete your cognitive assessment and health profile immediately.

How long after testing will I get my results?

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Your bloodwork will typically be available within a week of your blood draw. Once ready, you will recieve an email to view your results directly on our platform.

Who will have access to my results?

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We restrict access to results on a need-to-know basis. Namely, your results are available only to you, the ordering physician (who will contact you directly for any critical results), and your brain health expert if you are receiving coaching. Besides that, nobody has access to your health data.

Can I delete my data?

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Yes you can. BetterBrain exists to help you identify and understand your health data. We know that this is some of the most important information you have, and it is 100% yours - and nobody else's.

You can delete your data anytime you like by sending us an email at contact@betterbrain.com. Please know that we delete your data permanently. Once it's gone, we will not be able to get it back if you change your mind.

Will a clinician be reviewing my results?

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Yes, a medical doctor will review results from your lab tests and call you directly if there are any critical values in your results. Additionally, your results will be interpreted directly on our app and by your health coach, who is a Registered Nurse.

Who are the BetterBrain health coaches?

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Our head coach is a Registered Nurse and a specialist in neurology and intensive care. She has previously worked at the Mayo Clinic and the Emory University Health System, and was a frontline ICU nurse during the COVID-19 pandemic.

What time commitment does BetterBrain require?

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Our entire assessment process typically takes under an hour (~15 min for at-home blood test, <15 min for cognitive assessment, and <10 min for the health profile). However, the real work starts post-assessment. While many interventions are quick and easy (e.g., new supplement routine), others may require more effort (e.g., optimizing sleep). That said, we work hard to ensure you find things that are enjoyable and beneficial to many other aspects of your life.

How does BetterBrain's money-back guarantee work?

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We firmly believe in the effectiveness of our approach, so much so that we're prepared to stake our own resources on it. We will issue a 100% refund if you are unsatisfied for any reason; we just ask that you share which aspects you were unsatisfied with.

Is BetterBrain covered by insurance?

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BetterBrain is not reimbursable by insurance. This means we can offer you full transparency on our prices: no deductibles, no copays, no surprise bills.

Do I need a referral to join BetterBrain?

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No. BetterBrain is right for anyone looking to improve their brain health and brain performance. The sooner you set a baseline understanding for your body, the easier it will be to see your health trends and take action.

Where is BetterBrain available?

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BetterBrain is available in 47 states - all except NY, NJ, and RI. We are working to make BetterBrain available in those three states as well. Additionally, you can optionally choose at-home testing in select zip codes in 27 states and the District of Columbia.
Indicates states in which at-home testing is available for select zip codes
  • Arizona
  • California
  • Colorado
  • Delaware
  • DC
  • Florida
  • Georgia
  • Illinois
  • Indiana
  • Kansas
  • Massachusetts
  • Maryland
  • Michigan
  • Minnesota
  • Missouri
  • North Carolina
  • New Hampshire
  • Nevada
  • Ohio
  • Oklahoma
  • Oregon
  • Pennsylvania
  • Tennessee
  • Texas
  • Utah
  • Virginia
  • Washington
  • Wisconsin
Alabama
Alaska
Arizona
Arkansas
Califonia
Colorado
Connecticut
Delaware
Florida
Georgia
Hawaii
Idaho
Illinois
Indiana
Iowa
Kansas
Kentucky
Louisiana
Maine
Maryland
Massachusetts
Michigan
Minnesota
Mississippi
Missouri
Montana
Nebraska
Nevada
New Hampshire
New Mexico
North Carolina
North Dakota
Ohio
Oklahoma
Oregon
Pennsylvania
South Carolina
South Dakota
Tennessee
Texas
Utah
Vermont
Virginia
Washington
Washington, DC
West Virginia
Wisconsin
Wyoming
Other questions? Feel free to contact us